AG Tumormetabolismus (Tasdogan)
Distant metastasis is responsible for over 90% of deaths in cancer patients. Metastasis is an exceedingly complex process that involves an interplay between cancer cells and the microenvironment as well as intrinsic pathways in cancer cells. During metastasis, cancer cells undergo intravasation, transport through the circulatory system, arrest at a secondary site, extravasation, invasion of adjacent tissues, and growth in a secondary organ. Cancer cells undergo important metabolic changes that enable them to survive dissemination through the metastatic cascade.
Our labs focus is to better understand how metastatic melanoma cells adapt their metabolism at different stages of metastasis and to characterize the metabolic plasticity in metastatic melanoma tumors to dissect stage-specific metabolic adaptations for novel therapeutic strategies.
Distant metastasis is responsible for over 90% of deaths in cancer patients. Metastasis is an exceedingly complex process that involves an interplay between cancer cells and the microenvironment as well as intrinsic pathways in cancer cells. During metastasis, cancer cells undergo intravasation, transport through the circulatory system, arrest at a secondary site, extravasation, invasion of adjacent tissues, and growth in a secondary organ. Cancer cells undergo important metabolic changes that enable them to survive dissemination through the metastatic cascade.
Our labs focus is to better understand how metastatic melanoma cells adapt their metabolism at different stages of metastasis and to characterize the metabolic plasticity in metastatic melanoma tumors to dissect stage-specific metabolic adaptations for novel therapeutic strategies.
ERC Starting Grant
Emmy Noether Group Leaderㅤㅤㅤㅤㅤㅤㅤ
Peter Hofschneider endowed professor
Univ-Prof. Dr. med. Dr. rer. nat.
Alpaslan Tasdogan, MHBA
Oberarzt,
Institutsleiter Tumormetabolismus
Facharzt für Haut- und Geschlechtskrankheiten
Zusatzbezeichnung: Allergologie, Medikamentöse Tumortherapie
Funktionsoberärztin
Dr. med.
Lea Jessica Albrecht
Funktionsoberärztin,
Fachärztin für Haut- und Geschlechtskrankheiten
Zusatzbezeichnung: Medikamentöse Tumortherapie
Junior Group Leader
Dr. rer. nat.
Luiza Martins Nascentes Melo
Junior Group Leader
Postdoctoral Researchers
Dr. rer. nat.
Natalie Wagner
Postdoctoral Researcher
PhD
Amanda Pope
Postdoctoral Researcher
Physician Scientists
Dr. med.
Anna-Sophia Leven
Fachärztin für Haut- und Geschlechtskrankheiten
Dr. med.
Valeria Rieß
Assistenzärztin
Technician
Gabriele Allies
Senior Technician
Jonathan Krystkiewicz
Technician, Bachelor of Science
Nina Lapa
Technician, Bachelor of Scientist
Students
Flavia Carvalho Aguiar
Visiting PhD Student
Feyza Cansiz
PhD Student, Master of Science
Constantin Krempe
PhD Student, Master of Science
Tabea Massoth
PhD Student, Master of Science